SINDROM METABOLIK DENGAN RIWAYAT KONSUMSI ALKOHOL MENINGKATKAN RISIKO TERJADINYA CHRONIC KIDNEY DISEASE: STUDI KASUS KONTROL DI RS PANTI NIRMALA KOTA MALANG
Abstract
Chronic Kidney Disease (CKD) is a global public health problem with a high prevalence and incidence of kidney failure, poor prognosis, and has a large impact on morbidity, mortality, and socioeconomics of the community due to high treatment costs. Globally, CKD is the 12th leading cause of mortality and 17th for morbidity. There are several risk factors that are thought to increase the incidence of CKD, one of which is Metabolic Syndrome (SM). This study aims to determine the relationship between SM and the incidence of CKD at Panti Nirmala Hospital in Malang. The research design is case-control. The sample was 146 respondents, consisting of 73 case groups and 73 control groups. Data analysis using logistic regression. In the CKD group, the percentage of respondents with SM was 53.4% while in the group that did not suffer from CKD, the percentage of respondents with DM was 21.9%. It is known that after controlling for gender and age, respondents who have a history of consuming alcohol have an 11.9 times higher chance of developing CKD than respondents who do not have SM. It is recommended for the public to have regular health checks and change a healthy lifestyle, avoid consuming alcohol, and carry out regular health checks such as measuring blood pressure and blood sugar.
Keywords
Full Text:
PDFReferences
Christijani, R. 2019. Penentuan Diagnosis Sindrom Metabolik Berdasarkan Penilaian Skor Sindrom Metabolik dan NCEP ATP-III Pada Remaja. The Journal of Nutrition and Food Research. Vol 42(1), 21-28. https://doi.org/10.22435/pgm.v42i1.2418
Costa-Valle MT, Tonieto BD., Altkencht L., et al. 2018. Energy Drink and Alcohol Combination Leads to Kidney and Liver Alterations in Rats. Toxicol Appl Pharmacol. Vol 355. 138-146.
Crandall, J., Shamoon H. 2016. Diabetes Mellitus Dalam: Goldman L, Schafer AL, Enyunting. Goldmann-Cecil Medicine. Edisi ke 25. Philadelphia: Elsevier Saunders. Hlm 1542-1548.
De Oliveira HM Jr, Forniga FF, Alexandere Cda S. 2014. Clinical and Epidemiological Profile of Chronic Hemodialysis Patients in Joao Pessoa—PB. J.Bras Nefrol. 2014 Jul-Sep;36(3):367-74. English, Portuguese. PMID: 25317620.
Delima, Tjitra E, Tana L, Halim FS, Ghani L, Siswoyo H, et al. Risk Factors for Chronic Kidney Disease: A Case Control Study in Four Hospitals in Jakarta in 2014. Buletin Penelitian Kesehatan. 2017 Mar; Vol 45, No.1:17-26.
Driyah S., Oemiati R., Hartati NS. 2018. Prediktor Sindrom Metabolik: Studi Kohor Prospektif Selama Enam tahun di Bogor: Indonesia. Media Penelitian dan Pengembangan Kesehatan. Vol 29(3). https://doi.org/10.22435/mpk.v29i3.654
Hahr, A. J., & Molitch, M. E. 2015. Management of diabetes mellitus in patients with chronic kidney disease. Clinical diabetes and endocrinology, 1, 2. https://doi.org/10.1186/s40842-015-0001-9
Hecking M, Bieber BA, Ethier J, et al. 2014. Sex-Specific Differences in hemodialysis prevalence and practices and the male to female mortality rate: the dialysis Outcomes and Practice Patterns Study (DOPPS). PloS Med.
https://doi.org/10.1371/journal.pmed.1001750
Hill, N., L Oke, J., A. Hirst, J., O’ Callaghan, C. A. Lasserson, D., Richard Hobbs, F., et al. 2016 Global Prevalence Of Chronic Kidney Disease – A Systemic Review and Meta-Analysis.
Hosseini SM, Taghiabadi E, Abnous K., et al. 2017. Protective effect of Thymoquinone, the Active Constituent of Nigella Sativa Fixed Oils, against ethanol toxicity in Rats. Iran J Basic Med Science. Vol 20(8). 927-939.
Ikawati K., Chasani S., Suhartono S., dkk. 2018. Komponen Sindrom Metabolik sebagai Faktor Risiko Penyakit Ginjal Kronik Stadium Terminal (Studi di RSUP Dr.Kariadi dan RSUD Kota Semarang. Jurnal Epidemiologi Kesehatan Komunitas. Vol 3(1).18-28. https://doi.org/10.14710/jekk.v3i1.3213
Jha VK, Shashibhushan. 2018. Clinical Profile of Chronic Kidney Disease Patients in a Tertiary Care Hospital-An Observational Study. J.Nephrol Kidney Dis. Vol 2 (2):1016. Https://doi.org/10.36876/smjnkd.1016
Kang YU., Kim HY., Choi JS, et al. 2014. Metabolic Syndrome and Chronic Kidney Disease in an Adult Korean Population: results from the Korean National Health Screening. PloS ONE. Vol 9(5). E93795. Https://doi.org/10.1371/journal.pone.0093795
Kazancioglu, Rumyza. 2013. Risk Factors for Chronic Kidney Disease: an Update. Kidney International Supplements. 3: 368-371. https://doi.org/10.1038/KISUP.2013.79
Kementerian Kesehatan RI. (2017). Situasi Penyakit Ginjal Korinis. Pusat Data dan Informasi Kementerian Kesehatan RI: Jakarta
Kementerian Kesehatan RI. (2019). Hasil Utama RISKESDAS 2018. Badan Penelitan dan Pengembamngan Kesehatan: Jakarta 2.
Kovesdy, C. P., Furth, S., Zoccali, C., & World Kidney Day Steering Committee. 2017. Obesity and kidney disease: Hidden consequences of the epidemic. Indian journal of nephrology, 27(2), 85–92. https://doi.org/10.4103/ijn.IJN_61_17
Latchoumycandane C, Nagy Lem Mcintyre TM. 2014. Chronic Ethanol Ingestion in Duces Oxidative Kidney Injury Through Taurine-inhibitable Inflammation. Free Radic Biol Med. Vl.69.403-416
Philip McFarlane., David Cherney., Richard E. Gilbert., et al. 2018. Chronic Kidney Disease in Canada. Canadian Journal of Diabetes. https://doi.org/10.1016/j.jcjd.2017.11.004
Radica Z. Alicic., Michele T. Rooney., Katherine R. Tuttle. 2017. Diabetic Kidney Disease: Challenges, Progress, and Possibilities. Clin J Am Soc Nephrol. Vol 12: 2032–2045. https://doi.org/10.2215/CJN.11491116
Rivandi, J & Yonata, A 2015. ‘Hubungan Diabetes Melitus Dengan Kejadian Gagal Ginjal Kronik’, Majority Volume 4 Nomor 9 Desember 2015, diakses 17 Oktober 2018, http://juke.kedokteran.unila.ac.id/index.php/majority/article/view/1404
Rocco A, Compare D., Angrsani D., et al. 2014. Alcoholic Disease: liver and Beyond. World J Gastroenterol. Vol 20(40): 14652-16259.
Shirpoor A., Rezaei F., Fard A A., et al. 2016. Ginger Extract Protects Rat’s Kidneys against oxidative damage after Chronic Ethanol Administration. Biomed Pharmacother. Vol 84. 698-704.
Suandewi, DASA., Sugiarta, IGRSM, Astawa NY. 2020. Profil Penderita Chronic Kidney Disease (CKD) stadium 5 yang menjalani hemodialiss reguler di Rumah Sakit Umum Daerah (RSUD) Klungkung, Bali, Indonesia. Intisari Sains Medis. Vol 11 (22), 613-619. Https://doi.org/10.15562/ism.v11i2.624.
Yi Chin Lin., Yu Hsing Chang., Shao Yu Yang., et al. 2017. Update of Pathophysiology and Management of Diabetic Kidney Disease. Journal of the Formosan Medical Association. Vol 117; 662-675. https://doi.org/10.1016/j/jfma.2018.02.007
Refbacks
- There are currently no refbacks.
