Botani, Metabolit Sekunder dan Bioaktivitas Bangle (Zigiber montanum) (Review)

Marina Silalahi

Abstract

The use of plants as a medicine is sometimes doubted in modern medicine because it is not considered to have sufficient evidence. Zingiber montanum or also known as bangle is a of the types in the family Zingiberaceae which is used as a medicine, but an in-depth study of secondary metabolites and their bioactivity is still limited. This article aims to reveal botany, secondary metabolites, and bioactivity Z. purpureum so that it can be used as a basis for its use and development as traditional medicine and modern medicine. Studies on articles are based on various literary sources obtained off line or online in the form of journals, books, which can be downloaded using keywords, Zingiber, Zingiber montanum, secondary metabolites and bioactivities of Z. montanum. Rhizoma Z. montamun produces flavors and can be used to replace ginger (Zingiber officinale). As a traditional medicine in Asia, Z. montanum is used as a carminative drug, a stimulant for the stomach, diarrhea, colic, and headaches. Based on the bioactivity test in vitro and in vivo Z. montanum has pharmacological effects as anti-inflammatory, antimicrobial, analgesic and obesity.

Keywords

Analgesic; antimicrobial; zingiber montanum

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References

Bakkali, F., Averbeck, S., Averbeck, D., Idaomar, M. (2008). Biological effects of essential oils - A review. Food Chem. Toxicol. 46: 446-475.

Ballinger, A., and Peikin, S.I.R. (2002). Orlistat: Its current status as ananti-obesity drug. Eur J Pharm Sci 440:109-117.

Bhuiyan, M.N.I., Chowdhury, J.U., Begun, J. (2008). Volatile constituents of essential oils isolated from leaf and rhizome of Zingiber cassumunar Roxb. Bangladesh J. Pharmacol 3: 69-73.

Bordoloi, A.K., Sperkova, J., Leclercq, P.A. (1999). Essential oils of Zingiber cassumunar roxb. From Northeast India. J Essent Oil Res. 11: 441-445.

de Guzman, C.C. and Siemonsma, J.S. (1999). Spices Plant Resources of South-East Asia. Backhuys Publishers, Leiden

Han, A.R., Kim, M.S., Jeong, Y.H., Lee, S.K. Seo. E.K. (2005). Cyclooxygenase-2 inhibitory phenylbutenoids from the rhizomes of Zingiber cassumunar. Chem Pharm Bull 53:1466-1468.

Isrul, M., Alam, G., Sartini, Massi, N. (2017). New compound anti Mycobacterium tuberculosis from methanolic fraction of bangle rhizome (Zingiber cassumunar Roxb.). International Journal of PharmTech Research 10(1): 57-61.

Iswantini, D., Silitonga, R.F., Martatilofa, E., Darusman, L.K. (2011). Zingiber cassumunar, Guazuma ulmifolia, and Murraya paniculata extracts as antiobesity: in vitro inhibitory effecton pancreatic lipase activity. Hayati Journal of Biosciences 18(1): 6-10.

Kaewchoothong, A., Tewtrakul, S., Panichayupakaranant, P. (2012). Inhibitory effect of phenylbuta noid-rich Zingiber cassumunar extracts on nitric oxide production by murine macrophagelike RAW264.7 cells. Phytother Res. 26: 1789-1792.

Kanjanapothi, D., Soparat, P., Panthong A., Tuntiwachwuttikul, P., Reutrakul. V. (1987). A uterine relaxant compound from Zingiber cassumunar. Planta Med 53: 329-332.

Kress, W.J., Prince, L.M., Williams, K.J. (2002). The Phylogeny And A new classification of the gingers (Zingiberaceae): evidence from molecular data. American Journal of Botany 89(11): 1682-1696.

Larsen, K., Ibrahim, H., Khaw, S.H., Saw, L.G. (1999). Gingers of Peninsular Malaysia and Singapore. Kota Kinabalu: Natural History Publications, Malaysia

Ong-chai, S., Chotjumlong, P., Kongtawelert, P., Krisanapra kornkit, S. (2008). Zingiber Cassumunar Roxb. inhibits hyaluronan production in human oral fibroblasts. Chiang Mai Medical Journal 47(4): 177-187.

Pithayanukul, P., Tubprasert, J., Wuthi-Udomlert, M. (2007). In vitro antimicrobial activity of Zingiber cassumunar (Plai) oil and a 5% plai oil gel. Phytother Res. 21: 164-169.

Sabulal, B., Dan, M., Kurup, R., Pradeep, N.S., Valsamma, R.K., George, V. (2006). Caryophyl lene-rich rhizome oil of Zingiber nimmonii from South India: Chemical characterization and antimicrobial activity. Phytoche mistry 67: 2469-2473.

Shaari, K. (2015). Discovering Future Cures From Phytochemistry to Metabolomics. Universiti Putra Malaysia Press Serdang: 79 hlm.

Silalahi, M. (2014). The ethnomedicine of the medicinal plants in sub-ethnic Batak, North Sumatra and the conservation perspective, dissertation. Indonesia: Univer sitas Indonesia. 140 hlm.

Sivasothy, Y., Chong, W.K., Hamid, A., Eldeen, I.M., Sulaiman, S.F., Awang, K. (2011). Essential oils of Zingiber officinale var. rubrum Theilade and their antibacterial activities. Food Chem. 124: 514-517.

Sukatta, U., Rugthaworn, P., Punjee,S Chidchenchey, P., Keeratinijakal, V. (2009). Chemical composition and physical properties of oil fromplai (Zingiber cassumunar Roxb.) obtained byhydro distillation and hexane extraction. Kasetsart J. (Nat. Sci.) 43: 212- 217.

Tripathi, P., Dubey, N.K., Shukla, A.K. (2008). Use of some essential oils as post-harvest botanical fungicides in the management of grey mould of grapes caused by Botrytis cinerea. World J Microb Biotech. 24: 39-46.

Yanovski, S.Z., and Yanovski, J.A. (2002). Obesity. New England J Med 346: 591-602.

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